5 Mart 2010 Cuma

Galacto, lacto, milky

Gr. Gala : Milk (genitive; galakta) -->Gr. galaktikos (milky)
.............................................-->L. galaxia (Milky way; Via Lactea)

L. Lac : Milk (genitive; lactis) (Fr Lait)



lactation : Suckling
lactose: Milk sugar; < Lact + ose (sugar suffix; hexose, pentose, triose, glucose...)
lactic acid: Milk acid; an acid obtained from sour milk
galactose: Brain sugar; a constituent of lactose
galactin: prolactin

2 Mart 2010 Salı

Unconscious decision-making

Neuroscientists Daniel Kahneman and Amos Tversky received a 2002 Nobel Prize for their 1979 research that argued humans rarely make rational decisions.

People do indeed make optimal decisions—but only when their unconscious brain makes the choice.

You don't consciously decide to stop at a red light or steer around an obstacle in the road. Once we started looking at the decisions our brains make without our knowledge, we found that they almost always reach the right decision, given the information they had to work with

A very simple unconscious-decision test.

A series of dots appears on a computer screen, most of which are moving in random directions. A controlled number of these dots are purposely moving uniformly in the same direction, and the test subject simply has to say whether he believes those dots are moving to the left or right. The longer the subject watches the dots, the more evidence he accumulates and the more sure he becomes of the dots' motion.

Subjects in this test performed exactly as if their brains were subconsciously gathering information before reaching a confidence threshold, which was then reported to the conscious mind as a definite, sure answer.

The subjects, however, were never aware of the complex computations going on, instead they simply "realized" suddenly that the dots were moving in one direction or another. Human brain is wired naturally to perform calculations of this kind.

A probabilistic decision-making system has several advantages. The most important is that it allows us to reach a reasonable decision in a reasonable amount of time. If we had to wait until we're 99 percent sure before we make a decision, then we would waste time accumulating data unnecessarily. If we only required a 51 percent certainty, then we might reach a decision before enough data has been collected.

Another main advantage is that when we finally reach a decision, we have a sense of how certain we are of it—say, 60 percent or 90 percent—depending on where the triggering threshold has been set.

The findings are published in the Dec 26 2008 issue of the journal "Neuron"

http://www.sciencedaily.com/releases/2008/12/081224215542.htm

Delusions and right hemisphere

Delusions associated with consistent pattern of brain injury

How delusions arise and why they persist.

Patients with certain delusions and brain disorders reveals an injury to the frontal lobe and right hemisphere of the human brain. The cognitive deficits caused by these injuries to the right hemisphere, leads to the over-compensation by the left hemisphere, resulting in delusions.

The article entitled "Delusional misidentifications and duplications: Right brain lesions, left brain delusions" will appear in the latest issue of the journal of Neurology.

Problems caused by these right brain injuries include

~ impairment in monitoring of self

~ impairment in awareness of errors

~ incorrectly identifying what is familiar and what is a work of fiction

However, delusions result from the loss of these functions as well as the over activation of the left hemisphere and its language structures, that 'create a story', a story which cannot be edited and modified to account for reality.

Delusions result from right hemisphere lesions, but it is the left hemisphere that is deluded.

Often bizarre in content and held with absolute certainty, delusions are pathologic beliefs that remain fixed despite clear evidence that they are incorrect.

Most neurologic patients with delusions usually have lesions in the right hemisphere and/or bifrontal areas. For example, the neurological disorders of

~ Confabulation (incorrect or distorted statements made without conscious effort to deceive),

~ Capgras (the ability to consciously recognize familiar faces but not emotionally connect with them) and

~ Prosopagnosia (patients who may fail to recognize spouses or their own face but generate an unconscious response to familiar faces) result from right sided lesions.

The right hemisphere of the brain dominates

~ self recognition,

~ emotional familiarity and

~ ego boundaries.

After injury, the left hemisphere tends to have a creative narrator leading to excessive, false explanations. The resistance of delusions to change despite clear evidence that they are wrong likely reflects frontal dysfunction of the brain, which impairs the ability to monitor self and to recognize and correct inaccurate memories and familiarity assessments. Thus, right hemisphere lesions may cause delusions by disrupting the relation between and the monitoring of psychic, emotional and physical self to people, places, and even body parts. This explains why content specific delusions involve people, places or things of personal significance and distort ones relation to oneself.

In one study, nine patients with right hemisphere infarctions at a stroke rehabilitation unit had frequent delusion. While size of the stroke did not correlate when compared to the control group, the presence of brain atrophy was a significant predictor of delusions. When delusions occurred, it was usually caused by a right hemisphere lesion. Also, one study pointed out that delusional patients with Alzheimer's disease usually have significantly more right frontal lobe damage.

Other research showed that Reduplicative Paramnesia and Capgras syndrome cases with unilateral brain lesions strongly implicate the right hemisphere, usually the frontal lobe of the brain. Among 69 patients with Reduplicative Paramnesia, lesions were primarily in the right hemisphere in 36 cases (52%), bilateral in 28 (41%) and left hemisphere in 5 (7%) -- a sevenfold increase of right over left-sided lesions. Similarly in 26 Capras patients, lesions were primarily in the right hemisphere in 8 (32 %), bilateral in 16 (62 %) and left sided in 2 (7%)- a four-fold increase of right - over left-sided lesions. For both delusional syndromes, many bilaterial cases had maximal damage in the right hemisphere.

Among another study of 29 cases of delusional misidentification syndromes, all patients had right hemisphere pathology, while 15 (52 %) had left hemisphere damage. Fourteen had exclusively right hemisphere damage but none had isolated left hemisphere damage. When lateralized lesions are found, right hemisphere lesions are more common in other delusional misidentification and content specific delusions. Frontal lesions are strongly implicated in misidentification syndromes. Exclusively frontal lesions were associated with delusions in 10 of 29 (34.5) cases- four with right frontal and six with bifrontal lesions. None had lesions sparing the frontal lobes.

Source:
New York University School of Medicine
January 13th, 2009


adapted from
http://www.physorg.com/news151069576.html